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base-excision repair, AP site formation

Description

"The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone at the 5' side of the altered site to leave a gap which is subsequently repaired." [ISBN:0815316194]

Relations

part ofbase-excision repair

Parents

deoxyribonucleotide catabolic process

Identifier

GO:0006285
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Hierarchy

gene ontology entity
biological_process
cellular process
cellular metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
nucleotide metabolic process
deoxyribonucleotide metabolic process
deoxyribonucleotide catabolic process
base-excision repair, AP site formation
depurination
depyrimidination
deoxyribonucleoside diphosphate catabolic process
deoxyribonucleoside monophosphate catabolic process
deoxyribonucleoside triphosphate catabolic process
purine deoxyribonucleotide catabolic process
pyrimidine deoxyribonucleotide catabolic process
nucleotide catabolic process
deoxyribonucleotide catabolic process
base-excision repair, AP site formation
depurination
depyrimidination
deoxyribonucleoside diphosphate catabolic process
deoxyribonucleoside monophosphate catabolic process
deoxyribonucleoside triphosphate catabolic process
purine deoxyribonucleotide catabolic process
pyrimidine deoxyribonucleotide catabolic process
cellular catabolic process
nucleotide catabolic process
deoxyribonucleotide catabolic process
base-excision repair, AP site formation
depurination
depyrimidination
deoxyribonucleoside diphosphate catabolic process
deoxyribonucleoside monophosphate catabolic process
deoxyribonucleoside triphosphate catabolic process
purine deoxyribonucleotide catabolic process
pyrimidine deoxyribonucleotide catabolic process
metabolic process
cellular metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
nucleotide metabolic process
deoxyribonucleotide metabolic process
deoxyribonucleotide catabolic process
base-excision repair, AP site formation
depurination
depyrimidination
deoxyribonucleoside diphosphate catabolic process
deoxyribonucleoside monophosphate catabolic process
deoxyribonucleoside triphosphate catabolic process
purine deoxyribonucleotide catabolic process
pyrimidine deoxyribonucleotide catabolic process
nucleotide catabolic process
deoxyribonucleotide catabolic process
base-excision repair, AP site formation
depurination
depyrimidination
deoxyribonucleoside diphosphate catabolic process
deoxyribonucleoside monophosphate catabolic process
deoxyribonucleoside triphosphate catabolic process
purine deoxyribonucleotide catabolic process
pyrimidine deoxyribonucleotide catabolic process
cellular catabolic process
nucleotide catabolic process
deoxyribonucleotide catabolic process
base-excision repair, AP site formation
depurination
depyrimidination
deoxyribonucleoside diphosphate catabolic process
deoxyribonucleoside monophosphate catabolic process
deoxyribonucleoside triphosphate catabolic process
purine deoxyribonucleotide catabolic process
pyrimidine deoxyribonucleotide catabolic process
primary metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
nucleotide metabolic process
deoxyribonucleotide metabolic process
deoxyribonucleotide catabolic process
base-excision repair, AP site formation
depurination
depyrimidination
deoxyribonucleoside diphosphate catabolic process
deoxyribonucleoside monophosphate catabolic process
deoxyribonucleoside triphosphate catabolic process
purine deoxyribonucleotide catabolic process
pyrimidine deoxyribonucleotide catabolic process
nucleotide catabolic process
deoxyribonucleotide catabolic process
base-excision repair, AP site formation
depurination
depyrimidination
deoxyribonucleoside diphosphate catabolic process
deoxyribonucleoside monophosphate catabolic process
deoxyribonucleoside triphosphate catabolic process
purine deoxyribonucleotide catabolic process
pyrimidine deoxyribonucleotide catabolic process
catabolic process
cellular catabolic process
nucleotide catabolic process
deoxyribonucleotide catabolic process
base-excision repair, AP site formation
depurination
depyrimidination
deoxyribonucleoside diphosphate catabolic process
deoxyribonucleoside monophosphate catabolic process
deoxyribonucleoside triphosphate catabolic process
purine deoxyribonucleotide catabolic process
pyrimidine deoxyribonucleotide catabolic process
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