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spliceosome assembly

Description

"The aggregation and bonding together of the spliceosome, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions." [PMID:9476892]

Relations

part ofnuclear mRNA splicing, via spliceosome

Inverse Relations

nuclear mRNA branch site recognitionpart ofspliceosome assembly

trans assembly of SL containing precatalytic spliceosomepart ofspliceosome assembly

cis assembly of pre-catalytic spliceosomepart ofspliceosome assembly

mRNA splice site selectionpart ofspliceosome assembly

Parents

protein-RNA complex assembly

Identifier

GO:0000245

Hierarchy

gene ontology entity

biological_process

cellular process

cellular component organization and biogenesis

cellular component assembly

macromolecular complex assembly

protein-RNA complex assembly

	spliceosome assembly
	assembly of spliceosomal tri-snRNP
	cis assembly of pre-catalytic spliceosome
	formation of quadruple SL,U4,U5,U6 snRNP
	formation of translation initiation complex
	formation of translation initiation ternary complex
	formation of translation preinitiation complex
	miRNA-mediated gene silencing, miRNA loading onto RISC
	nuclear mRNA branch site recognition
	ribosome assembly
	RNA interference, siRNA loading onto RISC
	RNA interference, targeting of mRNA for destruction
	spliceosomal conformational changes to generate catalytic conformation
	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
	trans assembly of SL containing precatalytic spliceosome
	translational initiation

metabolic process

macromolecule metabolic process

macromolecular complex assembly

protein-RNA complex assembly

	spliceosome assembly
	assembly of spliceosomal tri-snRNP
	cis assembly of pre-catalytic spliceosome
	formation of quadruple SL,U4,U5,U6 snRNP
	formation of translation initiation complex
	formation of translation initiation ternary complex
	formation of translation preinitiation complex
	miRNA-mediated gene silencing, miRNA loading onto RISC
	nuclear mRNA branch site recognition
	ribosome assembly
	RNA interference, siRNA loading onto RISC
	RNA interference, targeting of mRNA for destruction
	spliceosomal conformational changes to generate catalytic conformation
	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
	trans assembly of SL containing precatalytic spliceosome
	translational initiation

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